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新型吡啶基吡唑酰胺类化合物的合成 被引量：1

Synthesis of Novel Pyridyl-pyrazole-5-carboxylic Acid Amide Compounds
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摘要 以2,3-二氯吡啶为起始原料,经过肼解、与马来酸二乙酯成环、卤代、氧化和水解得到关键中间体吡啶基吡唑甲酸,然后与二氯亚砜反应生成甲酰氯,最后与各种环氨作用生成吡啶基吡唑甲酰胺类化合物。 Key intermediate pyridinyl-1H-pyrazole-5-carboxylic acid was synthesized from the reaction of 2,3-dichloropyridine with hydrazine,which was then treated with diethyl maleate,then esterified through halogenation,oxidation,hydrolysis.Carbonyl chloride was synthesized by dichloro sulfoxide,and pyridinyl-1H-pyrazole-5-carboxylic acid amide compounds were synthesized by carbonyl chloride reacting with corresponding ammonia.
作者 郑毅 王俊芳 张应鹏 杨云裳
机构地区 兰州理工大学石油化工学院
出处 《应用化学》 CAS CSCD 北大核心 2010年第9期1105-1107,共3页 Chinese Journal of Applied Chemistry
基金 甘肃省自然科学基金(3ZS062-B25-017)资助项目
关键词 吡啶基吡唑羧酸 酰胺 合成 pyridyl-pyrazolecarboxylic acid amide synthesis
分类号 O622.5 [理学—有机化学]
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应用化学
2010年 第9期

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