摘要
目的探讨血浆肾素活性（ＰＲＡ）、醛固酮水平和高血压左室肥厚的关联性。方法２４入选的高血压病人根据超声心动图测定左室重量指数；放射免疫法测定ＰＲＡ和血浆醛固酮；动态血压监测２４时血压，统计分析其间的关联性。结果左室重量指数和醛固酮水平有紧密相关，而肾素活性相关无统计学上的显著性。单项回归分析醛固酮的数学方程为左室指数等于４７．６２＋０．５８醛固酮。多项回归分析入选醛固酮和ＰＲＡ，其公式为４２．５７＋０．５６醛固酮＋８．０５肾素活性。结论肾素－醛固酮系统的激活在高血压左室肥厚起重要作用。
Aim \ To investigate
the relationship of plasma renin activity(PRA),aldostrone level and left ventricular hypertrophy.\
Methods \ Left ventriclular mass index(LVMI) was examined with echocardiography in twenty
four hypertensive patients. PRA and aldosterone were examined wtih immunoradioassay.\
Results\ Strong relationship between aldosterone and LVMI(r=0824,P<0009) was found. The
regressive analysis shows LVMI=4762+058 aldo,and LVMI=4257+056 aldo+805 PRA.\
Conclusion \ The activity of RAAS is closely related to the formation of left ventricular
hypertrophy.\=
出处
《高血压杂志》
CSCD
1999年第2期108-110,共3页
Chinese Journal of Hypertension
关键词
高血压
左室肥厚
醛固酮
肾素活性
left ventricular hypertrophy
\ PRA activity
\ aldosterone
