膀胱鳞状细胞癌与浸润性膀胱移行细胞癌的临床对比分析

Clinical Features and Treatment of 10 Cases of Bladder Squamous Cell Carcinoma:Comparison with 34 Cases of Bladder Transitional Cell Carcinoma

目的对比分析膀胱鳞状细胞癌和浸润性膀胱移行细胞癌的临床特点,提高对膀胱鳞状细胞癌的认识及诊治水平。方法回顾性分析经术后病理检查证实为膀胱鳞状细胞癌的患者10例,与术后病理检查证实为浸润性移行细胞癌患者34例的症状、生化指标、肿瘤形态、预后等情况。结果 10例膀胱鳞癌患者与34例浸润膀胱移行细胞癌患者在首发症状为血尿、病程中出现肉眼血尿、病程中出现膀胱刺激症状、病程中是否出现贫血、尿中白细胞是否明显增多、肿瘤形态方面无统计学意义(P>0.05)。而在血尿程度、肿瘤分期上差异有统计学意义(P<0.05)。在手术治疗方式无明显差异的情况下一年内死亡率及一年后存活率间差异有统计学意义(P<0.05)。结论膀胱鳞状细胞癌具有恶性程度高、侵袭性强、预后差的特点,早期诊断及治疗对患者预后极为关键。

Objective To summarize the clinical features and treatment experiences of bladder squamous cell carcinoma （BSCC）.Methods We retrospectively analyzed the symptoms,biochemical indicators,morphology,and prognosis of BSCC in 10 pathologically confirmed patients.As a contrast,the clinical data of 34 cases of bladder transitional cell carcinoma （BTCC） were also analyzed.Results BSCC and BTCC had no significant differences in terms of initial symptoms （hematuria） as well as eye-visible hematuria,bladder-irritating symptoms,and anemia during their development （all P0.05）.However,there were some significant differences in terms of degree of hematuria and tumor staging （P0.05）.The one-year mortality and one-year survival were significantly different when basically similar treatment was applied.Conclusion BSCC is highly malignant and invasive,often resulting in poor prognosis.Early diagnosis and treatment are crucial for the prognosis of patients.