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端粒酶活性与慢性粒细胞白血病加速急变的关系 被引量:3

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摘要 端粒酶是一种特殊的核糖核蛋白聚合酶,起着维持真核细胞端粒长度的作用。近来发现正常体细胞基本没有端粒酶活性,而绝大多数肿瘤细胞表达端粒酶活性,表明端粒酶与细胞衰老和肿瘤发生有密切的关系[1]。我们应用PCRELISA技术对不同发展阶段慢性粒细胞白血病...
出处 《中华内科杂志》 CAS CSCD 北大核心 1999年第5期336-337,共2页 Chinese Journal of Internal Medicine
基金 国家自然科学基金
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  • 1朱旭贞,虞瑛姿,方永明,梁赟,吕庆华,徐荣臻.酪氨酸蛋白磷酸酶2高表达对p210bcr/abl诱导的慢性粒细胞白血病细胞增殖与凋亡抵抗的影响[J].中华医学杂志,2005,85(27):1903-1906. 被引量:3
  • 2王玮,孙秉中,药立波,刘新平.酪氨酸激酶抑制剂STI571治疗慢性粒细胞白血病的研究[J].实用医学杂志,2005,21(19):2108-2111. 被引量:1
  • 3郭小芳,乔宏,卢伟.慢性粒细胞白血病端粒酶活性检测的临床意义[J].青岛大学医学院学报,2006,42(3):197-199. 被引量:1
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