口腔糜烂型扁平苔藓与慢性肝病的临床研究

A Clinical Study of Oral Erosive Lichen Planus in Relation to Chronic Liver Disease

本研究对３２例口腔糜烂型扁平苔藓患者的肝酶学及病原学进行检测，结果发现，有７例患者（２１．８８％）的血清谷丙转氨酶（ＡＬＴ）和／或血清谷草转氨酶（ＡＳＴ）值升高，且这７例患者中有５例ＨＢｓＡｇ、ＨＢｅＡｇ和抗ＨＢＣ阳性。另有１例患者ＨＢｓＡｇ、ＨＢｅＡｇ和抗ＨＢＣ阳性、２例患者抗ＨＣＶ阳性，而血清酶水平未见升高。本研究结果提示，对口腔糜烂型扁平苔藓患者，除应注意询问相关病史外，还应常规进行肝功能和肝炎病毒检测。

Serum transaminase levels were found to be altered in 7 (21.88%) of 32 patients with oral erosive lichen planus. Among those patients with altered transaminase levels, five were found to be HBsAg,HBeAg and anti HBC positive. One patient with oral erosive lichen planus who was found to be HBsAg,HBeAg and anti HBC positive had not altered serum transaminase levls. Two patients with normal liver function test results were found to be anti HCV positive. Our results suggest that patients with oral erosive lichen planus should be asked about their relative history and determined their serum tramsaminase levels and HB(C)V as a routine laboratory test.