急性心肌梗死静脉溶栓治疗分析

Thrombolytic therapy in acute myocardial infarction

目的研究分析急性心肌梗死(AMI)患者静脉溶栓的治疗效果。方法回顾性分析2008年1月至2010年1月期间在我院接受静脉溶栓治疗的28例急性心肌梗死患者的临床资料。所有患者全部给予尿激酶100～150万U加生理盐水100ml静脉点滴30min滴完。结果 17例患者溶栓成功,再通率达60.71%,28例患者无一例死亡,全部转入内科进一步治疗,胸痛缓解19例,发生再灌注心律失常7例,不良反应为轻度出血,发生率14.29%。结论静脉溶栓可以降低患者死亡率,减少并发症,改善左室功能,改善预后。

Objective To investigate and analyze intravenous thrombolysis treatment in acute myocardial infarction（AMI） patients.Methods A retrospective analysis was performed from January 2008 to January 2010 in clinical data of 28 AMI patients who received thrombolytic therapy in our hospital.All the patients were intravenously injected with 1000～1500 thousand U of urokinase plus 100 ml normal saline,for 30 minutes.Results All 17 patients achieved successful thrombolysis,recanalization rate was 60.71%,no deaths occurred among 28 patients,who all transferred to the Medical Department for treatment.The chest pain relieved in 19 cases,reperfusion arrhythmias occurred in 7 cases,adverse events were mild bleeding,the incidence was 14.29%.Conclusion Intravenous thrombolysis can reduce mortality,reduce complications,improve left ventricular function,and improve prognosis.