米非司酮配伍米索前列醇用于高危妊娠引产疗效观察

Clinical effect observation of mifepristone and misoprostol on induced labour of high-risk pregnancy

目的观察米非司酮配伍米索前列醇用于高危妊娠引产的疗效。方法 52例患者随机分为观察组和对照组各26例。观察组给予米非司酮配伍米索前列醇引产,对照组给予依沙吖啶引产。观察2组引产效果、产后2h阴道出血量、引流产时间。结果观察组引产成功率为88.5%高于对照组的69.2%,差异有统计学意义(P<0.05)。观察组引流产时间短于对照组,阴道出血量≤月经量所占比例为69.2%高于对照组的23.1%,观察组阴道出血量>月经量所占比例为30.8%低于对照组的76.9%,差异均有统计学意义(P<0.05)。结论米非司酮配伍米索前列醇用于终止高危妊娠安全有效,值得临床推广应用。

Objective To observe the clinical effect of mifepristone and misoprosto on induced labour of high-risk pregnancy.Methods 52 cases were randomly divided into observation group and control group,26 cases of each.The observation group was given mifepristone and misoprostol for induced labour,while the control group received rivanol for induced labour.Observed two groups＇ induction effect,vaginal bleeding in 2 hours after delivery and abortion time.Results The successful induced labour rate of the observation group was 88.5% higher than 69.2% of the control group,and the difference was statistically significant（P0.05）.The abortion time of the observation group was shorter than that of the control group;The percentage of vaginal bleeding less than or equal to menstrual flow of the observasion group was 69.2% higher than 23.1% of the control group;The percentage of vaginal bleeding more than menstrual flow of the observation group was 30.8%,lower than 76.9% of the control group.All the differences were statistically significant（P0.05）.Conclusion Using mifepristone and misoprostol to terminate high-risk pregnancy is safe and effective,and is worth clinical popularizing and application.