通心络胶囊联合甲钴胺治疗糖尿病周围神经病变临床观察

Therapeutic effect of Tongxiuluo capsule combined with Mecobalamin on diabetic peripheral neuropathy

目的 观察通心络胶囊联合甲钴胺治疗糖尿病周围神经病变的临床疗效.方法 62例糖尿病周围神经病变患者随机分成治疗组和对照组,每组31例.对照组采用甲钴胺胶囊治疗,0.5 mg/次,3次/d;治疗组在对照组治疗的基础上加用通心络胶囊,2粒/次,3次/d,两组均以8周为一个疗程,然后判断疗效.结果 治疗组总有效率87.1%,对照组总有效率64.5%,两组比较差异有显著意义（P〈0.05）.结论 通心络胶囊联合甲钴胺胶囊治疗糖尿病周围神经病变安全有效.

Objective To observe the therapeutic effect of Tongxinluo capsule combined with Mecobalamin on diabetic peripheral neuropathy. Methods 62 patients with diabetic peripheral neuropathy were randomly divided into two groups. 31 patients in control group were treated with Mecobalamin capsule, 1 pill once, 3 times a day; The other 31 patients in treatment group, on the basis of control group, were treated with Tongxinluo capsule,2 pills once,3 times a day,with a treatment course of 8 weeks for both groups. The therapeutic effect was observed after one treatment courses. Results The totol effective rates in treatment group were 87.1%, which in control group were 64.5%, There was a significant difference between two groups （ P 〈0. 05 ）. Conclusion Tongxinluo capsule combined with Mecobalamin is safe and effective in treating diabetic peripheral neuropathy.