期刊文献+

帕瑞昔布钠对乳腺癌根治术使用布托啡诺患者静脉自控镇痛效果的影响 被引量:4

下载PDF
导出
摘要 目的探讨预先静脉注射帕瑞昔布钠对乳腺癌根治术使用布托啡诺患者自控静脉镇痛效果的影响。方法 40例ASAⅠ~Ⅱ级择期行乳腺癌根治术患者随机分为2组,P组麻醉诱导后切皮前静注帕瑞昔布钠40 mg;C组麻醉诱导后静注等量生理盐水。术毕均予布托啡诺患者静脉自控镇痛,观察术后4 h、8 h、12 h、24 h的VAS评分、Ramsay评分及静脉自控镇痛的不良反应。结果术后4 h、8 h、和12 h的VAS评分P组较C组显著减少(P均<0.05);术后4 h的Ramsay评分P组与C组比较有显著性差异(P<0.05);P组不良反应与C组比较有显著性差异(P<0.01)。结论静脉内预先给帕瑞昔布钠能显著提高布托啡诺术后镇痛效果,减少不良反应。
出处 《现代中西医结合杂志》 CAS 2010年第29期3764-3765,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
  • 相关文献

参考文献5

  • 1Jaw SP,Hoskins B,Ho IK.Opioid antagonists and butorphanol dependence[J].Pharmacol Biochem Behav,1993,44:497-500.
  • 2WHO Expert Committee on drug dependence.World Health Organization Expert Committee[J].World Health Organ Tech Rep Ser,2006,942:i1-i21.
  • 3Joshi G.Postoperative pain management[J].Int Anesthesiol Clin,1994,32:113-26.
  • 4Talley JJ,Bertenshaw SR,Brown DL,et al.N-(5-methyl-3-phenylisoxazol-4-yi)-phenyl sulfonyl propanamide,sodium salt,parecoxib sodium:a potent and selective inhibitor of Cox-2 for parenteral administration[J].J Med Chem,2000,43(9):1661-1663.
  • 5Kovac AL.Prevention and treatment of postoperative nausea and vo-miting[J].Drugs,2000,59(8):213.

同被引文献23

  • 1韩渊,于冰.乳腺癌术后皮下积液产生的原因及其对皮瓣坏死的影响[J].新疆医科大学学报,2005,28(9):865-867. 被引量:40
  • 2Choi Y J, Ko E Y, Han B K, et al. High - resolution ultra- sonographic features of axillary lymph node metastasis in pa- tients with breast cancer[J]. Breast, 2009, 18(2): 119.
  • 3Dalberg K, Johansson H, Signomldao T, et al. A ran domised study of axillary drainage and pectoral fascia preser vation after mastectomy for breast cancer[J ]. Eur J Surg On col, 2004, 30(6): 602.
  • 4Droeser R A, Frey D M, Oertli D, et al. Volume - con- trolled vs no/short- term drainage after axitlary lymph node dissection in breast cancer surgery: a meta - analysis [J ]. Breast, 2009, 18(2): 109.
  • 5Trombetta M, Valakh V, Julian T B, et al. Mammary fat necrosis following radiotherapy in the conservative manage- ment of localized breast cancer: does it matter[J]. Radiother Oncol, 2010, 97(1): 92.
  • 6Riest G,Peters J,Weiss M,et al.Preven-tive effects of perioperative parecoxib on post-discectomy pain[J].Br J Anaesth,2008,100(2):256-262.
  • 7Reuben SS, Ekman EF, Raghunathan K, et al. The effect of ey looxy genase inhibition on acute and chronic donor site pain af- ter spinal fusion surgery. Reg Anesth Pain Med,2006,31(1) 6-13.
  • 8Hinz B, Brune K. Cyclooxygenase-2 10 years later. J Pharma- col Exp Ther, 2002,300(2) : 367-375.
  • 9Ataie-Kachoie P, Pourgholami MH, Morris DL. Inhibition of the IL-6 signaling pathway: a strategy to combat chronic in- flammatory diseases and cancer. Cytokine Growth Factor Rev, 2013, 24(2):163-173.
  • 10Giamarellos-Bourboulis EJ, Spyridaki A, Savva A, et al. In- travenous paracetamol as an antipyretic and analgesic medica tion., the significance of drug metabolisn: J Pharmacol Sci, 2014, 124(2):144-152.

引证文献4

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部