摘要
干粉吸入装置(DPIs)是干粉吸入剂开发的核心,其设计的优劣直接影响到干粉肺部传递效率的高低。许多公司致力于DPIs的开发,已由第一代单剂量吸入装置发展到目前的多剂量主动吸入装置。本文综述了干粉吸入装置的应用现状、新一代装置的优点及未来干粉吸入装置的设计。
The inhaler device plays the most important role in successful development of dry powder inhalers（DPIs）. The efficiency of pulmonary drug delivery depends on the device. Efforts have been made by many companies for drug delivery systems to develop a wide range of DPIs from breath-actuated unit-dose devices to non-breath-actuated,multiple-dose inhalers. The status of the application of DPIs and the advantages and some designs of new inhalers are reviewed.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2010年第9期698-703,共6页
Chinese Journal of Pharmaceuticals
基金
江苏省抗肿瘤分子靶向药物研究重点实验室(BM2008202)
