蜂蜜对小鼠润肠通便作用的研究

Study of honey on mice laxative function

目的观察蜂蜜对小鼠的润肠通便作用。方法用复方地芬诺酯建立小鼠便秘模型,采用小鼠小肠推进实验、湿粪计数实验观察蜂蜜对致便秘模型小鼠的小肠内容物推进率、首次排便时间、6 h内排便粒数及排便总重量的影响。结果蜂蜜高、中剂量组均可明显增强小鼠小肠推进运动,增加小鼠粪便粒数及粪便重量,蜂蜜高剂量组还能显著缩短小鼠首粒黑便排出时间。结论蜂蜜对致便秘模型小鼠具有润肠通便作用。

Objective To investigate the laxative function of honey on mice.Methods The constipated model was established with the diphonxylate.Small intestinal propelling test and dejection counting test in mice were applied to observe the small intestinal propelling ratio,the time of the first dejection,the dejection amounts and weights in six hours.Results The high dose and middle dose of honey could improve intestinal peristalsis apparently,increase dejection amounts and weights.Moreover,the high dose of honey could shorten the time of the first dejection.Conclusion Honey has the laxative effect on constipated model mice.