每博量变异度指导围术期液体治疗的研究进展

Research Progress of Guiding Perioperative Fluid Therapy by Stroke Volume Uariability

每博量变异度（SVV）是液体管理的动态参数．基于全身麻醉机械通气的病人心和肺交互作用．并优于传统的静态指数（如CVP．PCWP等）。在机械通气下．SVV是计算一个呼暇循环的最大的每搏量（SVmax）与展小的每搏量（SVmin）之差值与每搏量平均值（SVmean）的比值．可预测心脏对容量负荷的反应以及与Frank-Starling曲线的关系。SVV近年来已作为指导围术期液体管理的重要方法应用在临床实践。SVV在预测补液反应中有较高的敏感性和特异性．但是仍有一些因素限制了其在临床实践的日常工作中的应用。

Stroke volume variability （SVV） is the dynamic parameters of fluid management, based on cardiopulmonary interactions in patients under generat anesthesia and mechanical ventilation, and is superior to traditional static indicators （such as central venous pressure, pulmonary capillary wedge pressure）. SW is calculated by taking the SVrnax - SVmin / SVmean over a respiratory cycle on mechanical ventilation, it can predict response to cardiac volume load and the relationship with Frank -Starling curve. In recent years SW has been implemented in clinical practice for guiding perioperative fluid management as an important method. SW has a very high sensitivity and specificity in predicting fluid responsiveness, while the usefulness of SVV in daily clinical practice is limited by several factors.