铁矿工人肺癌回顾性队列研究

Retrospective Cohort Study of Lung Canceramong Iron Miners

对１５个铁矿采矿工人的肺癌进行了回顾性队列研究。队列由１６９５１名１９７１年前入矿的男职工组成，观察期从１９８０年到１９８９年，失访７６０人（４５％）。队列内非接尘人群是接尘人群各群组的对照人群。接尘人群及其井下、露天、赤铁矿、磁铁矿各采矿群组中肺癌均无明显超量。但接尘人群分为非矽肺和矽肺两群组时，矽肺患者人群的肺癌显示超量。赤铁矿、磁铁矿、井下矿、露天矿各群组都再分为非矽肺和矽肺两群组时，除露天采矿（矽肺患者群组样本量很小）外，各矽肺组肺癌均显示超量。

A retrospective cohort mortality study was conducted for lung cancer among miners in 15 iron mines in China.The cohort included 16 951 male workers employed before 1971 and followed 1980 and 1989.760(4\^5%) of the cohort were lost to follow\|up.The analyses of cause\|specific mortality were performed,and the mortality of the dust\|exposed(miners)population was compared with the dust\|unexposed workers population within the cohort.No significant excess of lung cancer was found in 4 groups\_underground,open\|pit,hematite and magnetite exposure.But when the miners population and each of its groups were divided into two sub\|groups\_silicotics and non\|silicotics,significant excess of the lung cancer risk was observed in all silicotic subgroups.All non\|silicotic sub\|groups did not show statistically significant excess of the lung cancer risk.