82对双生子牙齿发育和萌出指标的遗传学分析

Genetic analysis of tooth development and eruption in 82 pairs of femalefemale twins

目的对牙齿发育指标和牙齿萌出指标进行遗传学分析。方法收集６～１２岁女性双生子８２对，通过ＤＮＡ指纹图进行卵型诊断。通过口腔检查和全口曲面断层片记录第三磨牙存在数、先天缺牙、上颌侧切牙畸形和萌出恒牙数，估算其遗传度。结果所测指标依遗传性由大到小依次为第三磨牙存在数、上颌侧切牙畸形、先天缺牙、萌出恒牙数。结论牙齿发育指标受遗传控制强于牙齿萌出指标。

Objective To study the heritability of tooth development and eruption. Methods 82 pairs of female female twins between 612 years old were collected. Twin zygosity diagnosis were made by DNAfingerprinting. The number of third molar present, hypodontia, upper lateral incisor malformation and the number of erupted permanent teeth were recorded by oral examination and panoramic radiographs, their heritabilities were calculated. Results According to the level of heritability, the dental traits were aligned as follows: the number of third molars present, the upper lateral incisor malformation, hypodontia and the number of erupted permanent teeth. Conclusion Though both the tooth development and its eruption were under genetic influence, the heritability of tooth development was far more than tooth eruption.