血浆脑钠肽与急性心肌梗死预后的关系

Relationship between Plasma Brain Natriuretic Peptide Level and Acute Myocardial Infarction Prognosis

目的探讨血浆脑钠肽(BNP)浓度的变化与急性心肌梗死(AMI)预后的关系。方法选取确诊为AMI的患者86例,入院后24h内检测血浆BNP浓度,所有患者均定期随访6个月,观察血浆BNP浓度与AMI预后的关系。结果与健康对照组相比较,AMI组血浆BNP浓度明显升高,且血浆BNP水平高的患者心血管事件发生率高(P<0.05)。结论 AMI患者血浆BNP浓度明显升高,血浆BNP水平可反映AMI的严重程度;BNP水平可作为心血管事件预测指标。

Objective To observe the relationship between the plasma level of brain natriuretic peptide （BNP）and the prognosis of acute myocardial infarction（AMI）. Methods We selected 86 cases of AMI,and measured the plasma BNP level within 24 hours after admission. All cases were followed up for six months. Results The plasma BNP level in the AMI group was significantly higher than that in the healthy group. The clinical cardiac events occurred more frequently in the cases of higher BNP level. Conclusion The plasma BNP level was increased significantly in AMI. The plasma BNP level in AMI might be a reliable biochemical marker which can objectively evaluate the degree and prognosis of the disease.