广州地区1688例正常儿童静脉血血小板参数参考范围调查

An Investigation on the Normal Reference Range for Platelet Parameters in Venous Blood of 1668 Healthy Children in Guangzhou Region

目的建立广州地区正常儿童静脉血血小板5项参数即PLT、MPV、PCT、PDW、P-LCR的正常参考范围。方法应用日本东亚公司的sysmex2100全自动血细胞分析仪采用仪器自动吸样的方式对居住在广州地区的1 688名正常儿童的静脉血血小板五项参数进行检测分析,并与国内部分报道结果进行比较。结果血小板五项参数的参考范围中PLT和PCT存在性别差异（P〈0.05）,男性参考范围为：PLT（174.66~406.30）×1012/L、PCT 0.156%~0.384%;女性参考范围为：PLT（125.49~425.05）×1012/L、PCT 0.134%~0.386%。其余指标参考范围为：MPV 6.9~12.1 fl,PDW 8.54%~17.98%、P-LCR 12.46%~40.54%。结论广州地区儿童女性PLT和PCT均值均低于男性,同性别各年龄阶段的指标也部分存在差异,4~8岁年龄段的血小板数为最高。

Objective To establish normal reference range for platelet parameters such as PLT、MPV、PCT、 PDW and P-LCR in venous blood of healthy adults in Guangzhou region.Method Four platelet parameters in venous blood of 1883 healthy children living in Guangzhou region were examined by Japanese sysmex2100 automated hematology analyzer by way of automated shaking up and sampling.Then the data were analyzed and compared with those reported in some other regions in China.Results Of the five platelet parameters,PLT and PCT in female were statistically lower than those in male（P0.05）while no statistical difference were found for other three.The normal reference range were as follows： PLT （174.66~406.30 for male,125.49~425.05 for female） ×1012/L,PCT 0.156 %~0.384% for male,0.134%~0.386% for female）,MPV 6.9~12.1 fl,PDW 8.54%~17.98%,P-LCR 12.46%~40.54%.Conclusion The normal reference range of the five platelet parameters for children in Guangzhou are not all coincidence for gender as well as age.