摘要
简述近十年来具有代表意义、开发成功的四种半合成及全合成他汀类药物的研究与开发新进展，包括其主要合成路线、临床特点、上市和销售情况及开发前景。
The new achievements in study and development of four representative semisynthetic and total synthetic ‘statin’ drugs HMG CoA reductase inhibitors were described, including the main routes of their syntheses, advantages in clinical uses and the prospects of their marketing and development.
出处
《药学进展》
CAS
1999年第2期65-71,共7页
Progress in Pharmaceutical Sciences
关键词
他汀类药物
LDL-C
高脂血症
合成
开发
HMG CoA reductase inhibitor Low density lipoprotein cholesterol Hyperlipidemia
