并发脑出血、脑梗死和心肌梗死的高血压患者降压药的利用

Current Status of Antihypertensive Drugs in Hypertensive Patients Who Were Complicated by Cerebral Hemorrhage, Cerebral Infarction and Myocardial lnfarction

了解并发脑出血、脑梗死（ＣＩ）和心肌梗死（ＭＩ）的高血压患者降压药的药物利用情况。方法运用药物流行病学的研究方法，对脑出血、ＣＩ和ＭＩ患者的抗高血压药的药物利用情况进行了横断面调查。结果住院前患者所服用过的降压药中老的复方制剂居首位（７３．７％），β受体阻断剂和利尿剂占少数，分别为２３．０％和１．１％。而住院期间患者所服用的降压药则以血管紧张素转换酶抑制剂（ＡＣＥＩ）和钙拮抗剂为主，分别是４５．９％和３５．６％，而复方制剂则为８．４％。结论住院前患者所服用过的降压药中仍以老的复方制剂为主，但是与８０年代的利用情况相比有所下降。由ＪＮＣＶ所推荐的一线降压药———β受体阻断剂和利尿剂占少数；

Purpose To have a better understanding of the use of antihypertensive drugs in hypertensive patients who were complicated by cerebral hemorrhage,cerebral infarction(CI) and myocardial infarction(MI). Methods We investigated the drug utilization of cerebral hemorrhage,cerebral infarction(CI) and myocardial infarction(MI) patients in the inpatient department in methods of pharmacoepidemiology. Results Our results showed that the most commonly used antihypertensive drugs were the traditional compound tablets(73.7%) before hospitalization.On the contrary,β blockers and diuretics were less used (23.0% and 1.1% respectively) During hospitalization,the most commonly used antihypertensive drugs were angiotensin converting enzyme inhibitors and calcium channel blockers(45.9% and 35.6% respectively),and traditional compound tablets were less (8.4%). Conclusions Although traditional compound tablets were less used as compared with that in 1980 s,they were still the most commonly used antihypertensive drugs before hospitalization.On the contrary,β blockers and diuretics were less used.During hospitalization,the most commonly used antihypertensive drugs were angiotensin converting enzyme inhibitors and calcium channel blockers.