摘要
探讨保守治疗异位妊娠以达到最低限度的外科干预和药物不良反应,提供新的治疗方法。方法采用宫腔注射氨甲喋呤(MTX),以血清β-绒毛膜促性腺激素(β-HCG)水平评价治疗效果,β-HCG下降至正常值(<3.1ng/ml)为治愈。结果16例中输卵管妊娠15例,宫角妊娠1例,均为未破裂型。治疗后72h血清β-HCG水平下降较治疗前有显著差异(P=0.033),治愈15例(93.7%),失败1例(6.3%)。住院天数4~22d,平均11.5d。结论对患者无损伤,药物不良反应小,方法简便。
Purpose Investigation of a new conservative procedure for the treatment of ectopic pregnancy in order to minimize surgical intervention and drug side effects. Methods ① Intrauterine injection of methotrexate (MTX).② Evaluation of therapeutic effects by measurement of serum β HCG level.Decline of serum β HCG following treatment indicating the therapy is effective,while return of β HCG to normal (<3.1 ng/ml) indicating the treatment is successful. Results 16 cases of ectopic tubal pregnancy are chosen for the present study.The results of treatment are:15 successful (93.7%),1 failure (6.3%). Conclusions The advantaged of intrauterine MTX injection for the treatment of ectopic tubal pregnancy are: no damage to the patient;mild drug side effects;simple and easy procedure.Therefore,cases of unruptured tubal pregnancy located in isthmus,interstitial or uterine cornual portins with serum β HCG less than 10 ng/ml are considered to be the priority of this treatment.
出处
《上海医科大学学报》
CSCD
1999年第3期182-183,共2页
Journal of Fudan University(Medical Science)