摘要
目的:总结分析儿童传染性单核细胞增多症(IM)的临床特点,降低临床漏诊误诊率。方法:回顾性分析我院儿科2004年1月-2008年12月收治的61例IM患儿临床资料。结果:全部病例均有发热且伴有不同程度咽峡炎。肝脏肿大12/61例(19.7%),脾脏肿大15/61例(24.6%),颈部淋巴结肿大58/61例(95.1%),伴有双眼睑水肿18/61例(29.5%),红色斑丘疹5/61例(8.2%)。出现溶血性贫血和血小板减少各1例(占3.2%)。33/61例(54.1%)出现肝功异常。3/29例心电图检查异常。结论:IM临床表现各异,可出现多脏器损害,大多预后良好,但病后应注意随访外周血变异淋巴细胞计数、血清EBV-VCA-IgM、肝肾功等检查,早期诊断,正确处理,避免漏诊误诊。
Objective:To summarize and analyze the clinical characteristics of Infectious mononucleosis (IM) in children,in order to decrease the missed diagnosis rate and misdiagnosis rate.Methods:The clinical data of 61 children patients with IM treated from January 2004 to December 2008 were analyzed retrospectively.Results:Fever occurred in all patients concomitant with different degree isthmitis,liver enlargement in 19.7%,spleen enlargement in 24.6%,cervical lymph node swelling in 95.1%,eyelids edema in 49%,erythematous papules in 8.2%,hemolytic anemia and thrombocytopenia in 3.2% (1 case respectively),abnormal liver function in 54.1% and abnormal ECG in 3/29.Conclusion:The clinical manifestations of IM differ from each other,and some cases can cause multiple organ damage,but the prognosis of a majority of patients was satisfactory.After this disease,the number of atypical lymphocyte (AL) in peripheral blood and the level of EBV-VCA-IgM in serum and liver and kidney function should be followed up.The IM in children should be diagnosed early and handle it correctly and avoid the missing diagnosis and erroneous diagnosis.
出处
《医学信息(中旬刊)》
2010年第10期2670-2671,共2页
Medical Information Operations Sciences Fascicule