摘要
为通过对氟康唑和二性霉素B治疗真菌性角膜溃疡的对照研究,探讨氟康唑治疗真菌性角膜溃疡的效果,对40例真菌性角膜溃疡患者分成甲、乙两组,每组20例,分别用氟康唑及二性霉素B(或联合酮康唑)进行治疗。结果:氟康唑组治愈17例,平均疗程16.5天,二性霉素B组治愈9例,平均疗程46.2天,两组比较治愈率有显著性差异(P<0.05;校正x2检验)。结论:氟康唑治疗真菌性角膜溃疡疗效优于二性霉素B。
Objective:To study the effect of fluconazole on fungal keratitis by a case control study of fluconazole and amphotericin B.Methods:40 cases of fungal keratitis were divided into two groups with 20 cases in each group,fluconazole and amphotericin B(or united with ketoconazole)were used for treatment of each group respectively.Results:17 cases were cured of the fluconazole group,and average period was 16 5 days.9 cases were cured of the amphotericin B group,and average perid was 46 2 days.There was a highly significant difference between the two groups(P<0 05;corrective x 2 test)Conclusion:Fluconazole is more effective than amphotericin B on treatment of fungal keratitis.
出处
《中国实用眼科杂志》
CSCD
1999年第5期282-283,共2页
Chinese Journal of Practical Ophthalmology