2型糖尿病患者骨密度的变化

LUMBAR SPINE AND PROXIMAL FEMUR MINERAL DETERMINATION BY DUAL ENERGY X RAY ABSORPTIOMETRY IN TYPE 2 DIABETES

本文采用了高精度的双能Ｘ线骨密度仪对３０例２型糖尿病男性患者和３０例年龄、性别和体重指数相匹配的非糖尿病健康者腰椎（Ｌ２～４）和股骨近端骨密度进行了检测，发现糖尿病患者腰椎和股骨近端骨密度明显降低（Ｐ＜０．０１～０．０５），同时对其骨密度的变化与年龄、糖尿病病程的关系进行了分析。提示老年糖尿病患者骨丢失率增加，且随着病程的延长骨量丢失以腰椎椎体为著。

In order to assess the skeletal density change of female type 2 diabetics,we measured lumbar spine (LS) and proximal femur bone mineral density (BMD) by dual energy X ray absorptiometry in 30 diagnosed patients with type 2 diabetes (DM),and 30 non diabetic healthy volunteers were matched in age sex body weight indexes as control group (CG).The results showed that LS and proximal femur BMD is significantly lower in DM than that in CG (P<0.01～0.05).We further analysed the influence of age and diabetic duration on BMD.Our analysis indicated that BMD in the aged is more extensively decreased than that in the young.The LS BMD in long term diabetics is significantily lower than that in short term ones;while proximal femur BMD changes are not significant.