摘要
目的探讨Ⅰ期子宫内膜癌的淋巴结转移率及行腹膜后淋巴结清除术的意义。方法对38例临床Ⅰ期子宫内膜癌患者临床、病理及随访资料进行回顾性研究,对照分析经行腹膜后淋巴清除术后,未发现淋巴转移者22例,FIGOⅠ期(A组),有淋巴结转移者6例,FIGO升级为Ⅲc期(B组)及未行腹膜后淋巴清除的10例(C组)。结果经腹膜后淋巴清除术的患者中214%(6/28)有腹膜后淋巴结转移,因此期别应上升为Ⅲc期,且腹膜后淋巴结转移与肿瘤细胞分级及肌层浸润深度相关(P<005)。在平均302个月的随访中,A、B两组无瘤生存率均为1000%(22/22及6/6),C组中2例肿瘤复发死亡。无瘤生存率为800%(8/10),比较有淋巴结转移的B组6例及C组中2例的生存率,差异有显著性(P<005)。结论对临床分期为Ⅰ期的子宫内膜癌患者应常规行全子宫、双附件切除加腹膜后淋巴结清除术。
Objective To evaluate the incidence of lymph
node metastasis and significance of lymphadenectomy in stage I endometrial cancinoma.
Metholds 38 patients with stage I endometrial carcinoma were divided into 3 groups and
retrospectively analysed.22 patients by lymphadenectomy were allotted to stage I endometrial
carcinoma according to FIGO(group A).6 patients were upstaged following
lymphadenectomy(groug B).And 10 patients were staged without lymphadenectomy(group C).
Results 214%(6/28)of patients were found to have retroperitoneal metastasis and therefore were
upstaged as stage c by lymphadenectomy.Metastases were directily related to the
differentiation of the tumor,depth of myometrial invasion.During the 302 months follow-up
period,tumor-free survival rates in group A and B were both 100%(22/22 and 6/6 respectively),In
group C,there were 2 recurrent patients and died of the diseases.The tumor-free survival rate
was 80%(8/10).There was a significant difference in tumor-free survival rate between group B
and C. Conclusions Retroperitoneal lymphadenectomy should be performed in all patients with
stage I endometrial carcinoma.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
1999年第6期363-364,共2页
Chinese Journal of Practical Gynecology and Obstetrics