栾树的化学成分

CHEMICAL CONSTITUENTS FROM THE LEAVES OF KOELREUTERIA PANICHLATA LAXM

目的：分离鉴定栾树（ＫｏｅｌｒｅｕｔｅｒｉａｐａｎｉｃｕｌａｔａＬａｘｍ）叶的化学成分。方法：９５％工业ＥｔＯＨ浸提，硅胶柱色谱分离，ＩＲ，ＭＳ，ＵＶ，１ＨＮＭＲ，１３ＣＮＭＲ等方法确定结构。结果：分得１４个化合物，分别为对二没食子酰乙酯（ｅｔｈｙｌｐｄｉｇａｌａｔｅ）（１），间二没食子酰乙酯（ｅｔｈｙｌｍｄｉｇａｌａｔｅ）（２），对二没食子酸（ｐｄｉｇａｌｏｙｌａｃｉｄ）（３），间二没食子酸（ｍｄｉｇａｌｏｙｌａｃｉｄ）（４），２″没食子酰基槲皮素苷（ｑｕｅｒｃｉｔｒｉｎ２″ｇａｌａｔｅ）（５），没食子酸（ｇａｌｏｙｌａｃｉｄ）（６），没食子酸乙酯（ｅｔｈｙｌｇａｌｏｙｌａｃｉｄ）（７），鞣花酸（ｅｌａｇｉｃａｃｉｄ）（８），槲皮苷（ｑｕｅｒｃｉｔｒｉｎ）（９），金丝桃苷（ｈｙｐｅｒｉｎ）（１０），山奈酚３Ｏ鼠李糖苷（ｋａｅｍｐｆｅｒｏｌ３Ｏｒｈａｍｎｏｓｉｄｅ）（１１），２″没食子酰金丝桃苷（ｈｙｐｅｒｉｎ２″ｇａｌａｔｅ）（１２），β谷甾醇（βｓｉｔｏｓｔｅｒｏｌ）（１３），β谷甾醇３Ｏ葡糖苷（βｓｉｔｏｓｔｅｒｏｌ３Ｏｇｌｕｃｅｒｏｓｉｄｅ?

AIM: Isolation and structural elucidation of the constituents from leaves of the Chinese medicinal plant Koelreuteria paniculata Laxm. METHODS: The leaves were extracted with 95% EtOH percolation and the crude extracts were purified by using silica gel chromatography. IR, UV, MS, 1H and 13CNMR spectra were employed for structural identification. RESULTS: Three new compounds named ethylpdigallate ( 1 BZ), ethylmdigallate ( 2 ), pdigalloyl acid ( 3 ), together with eleven known compounds mdigalloyl acid ( 4 ), quercitrin2gallate ( 5 ), galloyl acid ( 6 ), ethyl galloyl acid ( 7 ), ellagic acid ( 8 ), quercitrin ( 9 ), hyperin ( 10 ), kaempferol3Orhamnoside ( 11 ), hyperin2gallate ( THZ12 ),sitosterol ( 13 ) and sitosterol 3Oglucoside ( 14 ) were isolated. CONCLUSION: Ethylpdigallate ( 1 ), ethylmdigallate ( 2 ) and pdigalloyl acid ( HZ3 ) were new compounds, and 4, 5, 8 12 and 14 were known compounds unreported previously from this plant.