长骨骨化性纤维瘤的临床分析

Clinical analysis of 12 cases of long bone ossifying fibromas

１２例长骨骨化性纤维瘤，１１例经手术切除病灶及其硬化边缘，应用５０％氯化锌涂抹骨腔杀灭残存的瘤细胞，自体骨或加入少量人工骨植骨；１例行病变骨段切除。结果表明，随访３～１４年，２例复发，经再次手术后５～１４年未复发。本组病例复发率低，疗效满意，切除肿瘤硬化边缘能有效地防止复发。

Twelve cases of ossifying fibroma of long bones, the lesions in 11 cases were resected with their sclerotic margin. Inactivation of the tumor cells within bone cavity was applied 50% Zinc Chloride, and autogenous bone grafts were applied with or without a few man made bones. One case was treated by en bloc resection of the lesion. Follow up for 3～14 years revealed that 2 cases recurred, and secondary operation was performed. After that follow up for 5～14 years revealed no recurrence. Recurrence rate of these cases was low and the effect of treatment was satisfactory. This kind of lesion showed the features of its aggresive growth and proneness to recur after operation. The authors consider that resection of the lesion including its sclerotic margin was effective to prevent recurrence.