氧驱动雾化吸入普米克令舒和可必特治疗毛细支气管炎喘憋发作临床疗效观察

Clinical effective observation of oxygen-powered atomization inhalation with pulmicort respules and combivent on treating wheezes in bronchiolitis

目的:观察普米克令舒联合可必特经氧驱动雾化吸入治疗毛细支气管炎喘憋发作的疗效。方法:146例毛细支气管炎患儿均予综合治疗,分三组,治疗组按随机分为1,2两组,并分别氧驱动雾化吸入Ⅰ,Ⅱ号各48例,对照组50例予以静脉滴注氨茶碱及氢化可的松琥珀酸钠。观察各组在疗效、临床症状缓解时间及住院时间的比较。结果:两治疗组与对照组比较,治疗组显效率,临床症状缓解时间优于对照组(P<0.01),且住院时间治疗组均短于对照组(P<0.01),而治疗组中又以雾化1组(普米克令舒加可必特)作用更显著。结论:6～8L/min氧驱动雾化吸入普米克令舒和可必特是治疗毛细支气管炎喘憋发作的有效方法,疗效显著,值得在基层医院推广。

Objective：To discuss the efficacy of oxygen-powered atomization inhalation with pulmicort respules and combivent on treating wheezes in children bronchiolitis.Methods：146 children cases of bronchiolitis were cured by combined therapy and divided randomly into three groups：the treatment groupⅠ （n=48） and the treatment groupⅡ （n=48） treated with oxygen-powered atomization inhalation,the control group （n=50） treated with aminophylline and hydrocortisone sodium succinate by intravenous drip.To observe the difference in efficacy,time of symptomatic relief and length of stay among the three groups.Results：The time of symptomatic relief in the treatment groups was significantly shorter than that in the control group（P0.01）.The efficacy in the treatment groupⅠ（treated with pulmicort respules and combivent） was more significant than that in the treatment groupⅡ.Conclusion：The method of oxygen-powered atomization inhalation with pulmicort respules and combivent （6~8L/min） on treating wheezes in children bronchiolitis is proved to be reliable and worth being spread in primary hospital.