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肾移植术后肺部感染28例临床分析 被引量:1

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摘要 目的:探讨肾移植术后肺部感染的原因、诊断与治疗。方法:对本院28例肾移植术后肺部感染患者的临床资料进行回顾分析。结果:28例患者中确诊细菌感染47例次(47%),巨细胞病毒(cytomegalovirus,CMV)23例次,真菌17例次,结核杆菌5例次,卡式肺囊虫2例次,6例次未找到明确病原菌。感染的中位时间为移植术后79.50d,平均时间为移植术后84.64d;感染时间分布为:术后3个月之内14例,3~6个月10例,6个月之后4例。28例肺部感染患者中并发急性肺损伤急性呼吸窘迫综合征16例,其中13例行机械通气治疗,12例治愈。本组28例患者中,共治愈24例,死亡4例。结论:肾移植术后肺部感染多发生于术后半年尤其是3个月内,病情发展迅速,发展为ARDS后治疗难度加大,预后差,感染病原体多样,确诊困难,影像学检查意义非常必要。早期联合抗细菌、抗病毒、抗真菌及抗支原体治疗,及时调整免疫治疗方案,有低氧血症表现时需无创鼻导管/面罩吸氧,加强营养及患者自身抵抗力,适时予以呼吸机辅助呼吸是救治成功的关键。
出处 《现代医药卫生》 2010年第20期3078-3080,共3页 Journal of Modern Medicine & Health
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  • 1Kall et R H. Evidence Based Management at Acute Lung Injury and Acute Respiretory Dist ress Syndrome [J].Respire Care,2004,49 (7) :793.
  • 2Dreyfuss,Saumon G.Ventilator2induced Lung Injury [J].Am J Respir Crit Care Med, 2008,15(7) : 294.
  • 3范连慧,刘龙,向军,杨宏伟,李昕,曹志强.187例肾移植受者死亡原因分析[J].中华器官移植杂志,2005,26(8):461-463. 被引量:33
  • 4徐廷昭,郑凯,谭建明,吴卫真,杨顺良.肾移植中生物免疫制剂应用与术后肺部感染的关系[J].中华泌尿外科杂志,2007,28(2):95-97. 被引量:11
  • 5Luukkainen T,Pakarinen P,Toivonen J.Progestin2releasing in2 trauterine svstem[Jl.Semi Reorod Med,2001,19(4):355.
  • 6中华医学会呼吸病学分会.急性肺损伤/急性呼吸窘迫综合征的诊断标准[J].中华结核和呼吸杂志,2000,23(4):203-203.

二级参考文献20

  • 1杨顺良,谭建明,吴卫真,林文洪,徐廷昭,朱凌峰,王栋.致敏肾移植受者术前单次大剂量抗胸腺细胞球蛋白诱导治疗的价值[J].中华泌尿外科杂志,2004,25(11):746-749. 被引量:4
  • 2徐廷昭,沈瑞雄,谭建明,汪家兴,吴卫真,杨顺良,王栋.肾移植患者并发严重肺部感染的诊断与治疗[J].临床泌尿外科杂志,2004,19(11):670-672. 被引量:9
  • 3Fishman JA, Rubin RH. Infection in organ-transplant recipients. N Engl J Med, 1998, 338: 1741-1751.
  • 4Uchida K, Nakayama H, Yoshida K, et al. Opportunistic pneumonia after kidney transplantation. Nihon Kokyuki Gakkai Zasshi, 2001, 39: 166-171.
  • 5Pacholczyk MJ, Lagiewska B, Meszaros J, et al. Bacterial infections transmitted from the donor: antibiotic prophylaxis in the donor, Transplant Proc, 1996, 28:184-185.
  • 6Adams HP, Dawson G, Coffman TJ, et al. Stroke in renal transplant recipients. Arch Neurol, 1986, 43: 113-115.
  • 7Kavanagh D, Morris ST, Northridge DB, et al. Electrocardiogram and outcome following renal transplantation. Nephron,1999, 81: 109-110.
  • 8Lindholm A, Albreehtsen D, Frodin L, et al. Ischemic heart disease - major cause of death and graft loss after renal transplantation in Scandinavia. Transplantation, 1995, 60: 451-457.
  • 9Candinas D, Keusch G, Conrad B, et al. A 20-year follow-up of cadaveric kidney allotransplantation. Transplant Proc, 1992,24: 2711-2713.
  • 10Zeevi A, Pavlick M, Lombardozzi S, et al. Immune status of recipients following bone marrow-augmented solid organ transplantation. Transplantation, 1995, 59:616-620.

共引文献106

同被引文献20

  • 1滕琳,刘婷,李美香,吴立平,甄永强.肾移植术后并发肺部感染10例[J].中国感染与化疗杂志,2010,10(4):270-272. 被引量:3
  • 2闵志廉,朱有华,何长民,贺宗理,孟钢,王卓伟,齐隽,王立明,郑军华,徐丹枫,王亚伟,任吉忠,周梅生,余加仁.尸体肾移植1011例次的临床报告[J].第二军医大学学报,1994,15(5):401-406. 被引量:7
  • 3Sia IG, Paya CV. Infectious complications following renal transplantation[J]. Surg Clin North Am, 1998, 78(1): 95-112.
  • 4Briggs JD. Cause of death after renal transplantion[J]. Nephrol Dial Transplant, 2001, 16(11): 1545-1549.
  • 5Rubin RH. The impact of mtectuous on the outcome of transplantation[J]. Transplant Proc, 1991, 23(4): 2068-2074.
  • 6Santos CAQ, Brennan DC. Infections in kidney transplant recipien[M]//McKay DB, Steinberg SM. Kidney transplantation: a guide to the care of kidney transplant recipients. New York: Springer, 2010: 277-309.
  • 7John GT, Shankar V, Abraham AM. Risk factors for post transplant tuberculosis[J]. Kidney Int, 2001, 60(3): 1148-1153.
  • 8Kalra V, Agarwal SK, Khilnani GC, et al. Spectrum of pulmonary infections in renal transplant recipients in the tropics: a single center study[J]. Int Urol Nephrol, 2005, 37(3): 551-559.
  • 9Chen G, Zhang Z, Gu J, et al. Incidence and risk factors for pulmonary mycosis in kidney transplantation[J]. Transplant pro, 2010, 42(10): 4094-4098.
  • 10Hoyo I, Linares L, Cervera C. Epidemiology of pneumonia in kidney transplantation[J]. Transplant Proc, 2010, 42(8): 2938-2940.

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