国产钛镍合金血管支架的生物相容性研究

The Biocompatibility of Chinese Nitinol Alloy Intravascular Stent

采用国产钛镍形状记忆合金制成４ ｍ ｍ 内径的血管支架，通过导管置入８ 只正常犬的双侧髂动脉。观察１～６ 个月，发现支架表面为一层新生内膜覆盖，光镜及电镜观察新生内膜表层为血管内皮样细胞。国产钛镍合金血管支架有很好的生物相容性。

The aim of this study was to evaluate the biocompatibility of Chinese nitinol alloy intravascular stent. Sixteen Chinese nitinol alloy intravascular stents with 4mm ID were implanted in the left and right iliac arteries of 8 normal dogs and were observed for one to six months. The results showed that the stents implanted were completely covered by a thin layer of the neointima after one month and the surface of neointima was covered by a monolayer of endothelium like cells.These suggest that the Chinese nitinol alloy has very good biocompatibility.