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不同人群血脂与血小板数量、平均血小板体积的相关性 被引量:9

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摘要 目的研究不同人群血脂与血小板数(PLT)和平均血小板体积(MPV)的相关性,探讨血脂对PLT和MPV的影响。方法以1501例正常血脂的体检人群作为对照组,分析335例单纯性血脂异常人群、156例冠心病(CAD)患者、85例心肌梗死(MI)患者,以及85例MI患者中的28例急性心肌梗死(AMI)患者阿司匹林治疗前后的甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、PLT和MPV的变化。结果高血脂组占体检总数的18.3%。PLT在高血脂组变化无统计学意义,在CAD组和MI组显著下降(P<0.05,P<0.01),在AMI组经治疗后恢复不明显。MPV在高血脂组和CAD组升高(P<0.05),在MI组显著下降(P<0.01),在AMI组经治疗后显著恢复升高(P<0.01)。结论血脂与MPV有明显相关性,MPV可以作为血脂异常诱发血小板活化并导致心血管疾病发生发展的监测指标。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2010年第17期2409-2411,共3页 Chinese Journal of Gerontology
基金 安徽省教育厅自然科学课题(KJ2008B307)
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二级参考文献22

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