癌性创伤后应激障碍的神经影像学研究

Research of functional neuroimaging of cancer-related post-traumatic stress disorder

随着医学技术的发展,癌症患者的存活时间不断延长,癌症引起的慢性应激损害即癌性创伤后应激障碍(PTSD)也日益引起人们的重视。癌性PTSD与普通PTSD有显著差异,各种神经影像学工具,如磁共振成像(MRI)、正电子发射断层扫描(PET)及单光子发射计算机断层扫描(SPECT)等,为深入研究与肿瘤相关的精神异常现象的发生机制提供了强有力的技术支持,极大地促进了该领域的发展。文章就神经影像学在与肿瘤有关的PTSD研究中的应用进行综述。

With the rapid development of modern medical techniques,the survival time of patients with cancer has been greatly extended,and chronic stress injury induced by cancer （cancer-related post-traumatic stress disorder,PTST） has aroused increasingly more attention.There were significant differences between cancer-related PTST and traditional PTSD.Modern neuroimaging techniques,such as magnetic resonance imaging （MRI）,positron emission tomography （PET） and single proton emission computed tomography （SPECT）,are powerful tools for research of mechanisms of tumor-related mental disorders.The application of neuroimaging in research of tumor-related PTSD is reviewed in this paper.