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脂联素血管保护机制研究进展 被引量：5

Research progress of vascular protection mechanism of adiponectin
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摘要 脂联素是一种由脂肪细胞分泌的血浆蛋白,具有心血管保护作用。脂联素通过多种信号通路,发挥抗炎、抗氧化、抗动脉粥样硬化、改善微循环及双向调节血管新生的作用。文章就脂联素血管保护机制的研究进展作一综述。 Adiponectin is an abundant plasma protein secreted from adipocytes that elicits protective effects in the vasculature and myocardium.Adiponectin suppresses oxidative stress,inhibits inflammatory signaling cascades,ameliorates microvascular circulation and regulates angiogenesis via multiple signal pathways.The research progress of vascular protection mechanism of adiponectin is reviewed in this paper.
作者 张凌娟 苏青
机构地区 上海交通大学医学院附属新华医院内分泌科
出处 《上海交通大学学报（医学版）》 CAS CSCD 北大核心 2010年第9期1164-1167,共4页 Journal of Shanghai Jiao tong University:Medical Science
关键词 脂联素 动脉粥样硬化 信号通路 adiponectin atherosclerosis signal pathway
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献24

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同被引文献54

  • 1Virani SS, Polsani VR, Nambi V. Novel markers of inflammation in atherosclerosis [ J]. Curr Atheroscler Rep, 2008, 10 (2): 164.
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引证文献5

二级引证文献10

上海交通大学学报（医学版）
2010年 第9期

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