西藏高原地区藏族人群血脂水平分析

The analysis of levels of blood lipid of Tibetans in plateau region Tibet

目的 比较分析藏族和世居拉萨汉族健康人群血脂水平和血脂异常变化状况.方法 用全自动生化分析仪检测拉萨市13 037名成年健康体检人群（藏族8 163名,汉族4 874名）空腹血脂水平（TC、TG、HDL-C、LDL-C） 比较分析藏族与世居拉萨汉族不同年龄组（藏族：＜25岁组298名、25岁～组1 136名、35岁～组2 039名、45岁～组2 119名、55岁～组1 580名、65岁～组905名、≥75岁组86名,汉族：＜25岁组307名、25岁～组1 254名、35岁～组1 874名、45岁～组1 022名、55岁～组272名、65岁～组129名、≥75岁组16名）、不同性别组（藏族：男4 505名、女3 658名,汉族：男2 976名、女1 898名）之间血脂水平差异.结果 藏族TC、HDL-C和LDL-C分别为（5.07±1. 10）、（1.54±0.49）和（3.33±1.31）mmol/L,世居拉萨汉族分别为（4.60±0.98）、（1.45±0.44）和（2.85±1.08）mmol/L,藏族各年龄组均高于世居拉萨汉族（t值分别为24.78、10,53和21.46,P均＜0.05） TG藏族为1.38（0.20～2.99）mmol/L,世居拉萨汉族为1.54（0.20～2.99）mmol/L,世居拉萨汉族各年龄组均高于世居拉萨藏族（F=224.88,P＜0.05）.藏族总高血脂率为75.32%,世居拉萨汉族总高血脂率为69.02% 男性为78.56%,女性为65.42%.民族、性别间差异均有统计学意义（x2分别为9.678、44.138,P均＜0.05）.结论 藏族人TC、LDL-C水平和高血脂率高于长期生活在拉萨地区的汉族人群.

Objective To analyze the level of blood lipid in healthy Tibetans and Han natives in Lasa through the detection of serum lipids. Methods The serum TC, LDL-C, HDL-C and TG were detected by Hitachi 7060 automatic biochemical analyzer in 13 037 healthy adults （8 163 Tibetan individuals and 4 874 Han individuals）. After that, all data were statistically analyzed by age （Tibetan：298 cases of 〈25 year-old group, 1 136 cases of 25-year-old group, 2 039 cases of 35-year-old group, 2 119 cases of 45-year-old group, 1 580 cases of 55-year-old group, 905 cases of 65-year-old group, 86 cases of ≥75 year-old group Han population：307 cases of 〈25 year-old group, 1 254 cases of 25-year-old group, 1 874 cases of 35-year-old group, 1 022 cases of 45-year-old group, 272 cases of 55-year-old group, 129 cases of 65-year-old group, 16 cases of≥75 year-old group）, sex （Tibetan： men 4 505 cases, women 3 658 cases Han population：men 2 976 cases,women 1 898 cases）. Results The average TC, HDL-C and LDL-C levels of Tibetans were （5.07 ± 1.10）, （ 1.54 ±0. 49） and （3.33 ± 1.31 ） mmol/L respectively while the average levels of Han natives in Lasa were （4. 60 ± 0. 98 ）, （ 1.45 ± 0. 44 ） and （ 2. 85 ± 1.0g ） mmol/L, which showed the levels of the Tibetans were higher than the Han natives in each age group（t =24. 78, 10. 53,21.46, P〈0.05）. The TG levels was 1.38 （ 0. 20-2. 99 ） mmol/L in Tibetans and 1.54 （0.20-2.99）mmol/L in Han natives （ F = 224. 88, P 〈 0. 05 ）. The prevalence of total dyslipidemia was 75. 32% in Tibetans and 69. 02% in Han natives of Lasa. The prevalence of total dyslipidemia was 78. 56% in male and 65.42% in female. There were significant differences in both ethic and sex groups（x2 = 9. 678, 44. 138,P 〈0. 05）. Conclusion The TC, LDL-C levels and prevalence of dylipidemia in Tibetans are higher than the Han residents in Lasa.