拉萨市藏、汉民族血脂水平的比较

A comparative study on serum lipid levels of Tibetan and Han people in Lhasa,China

目的调查分析拉萨市藏、汉民族间血脂水平及其异常检出率的差异,为该地区血脂异常症的预防提供客观依据。方法选取拉萨市藏(Tibetan,T)、汉民族(Han,H)1 228例体检人群为调查对象,其中藏族559例,汉族669例,按血脂测定标准化方法测定的血清总胆固醇(total cholesterol,TC)、三酰甘油(triglycerin,TG)、高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)及低密度脂蛋白胆固醇(low-density lipoproteincholesterol,LDL-C)4项指标的血脂水平;按2007年《中国成人血脂异常防治指南》将研究对象分为4个年龄组,界定4项血脂异常标准值,比较藏、汉民族各年龄组血脂异常检出率的差异。采用协方差分析和χ2检验比较两民族间血脂存在的差异。结果汉族TG水平高于藏族(P≤0.001),HDL-C水平低于藏族(P<0.001);藏族TC和LDL-C水平均高于汉族(P<0.001、P=0.013)。藏族男性青年组、中年组、老年前期组TC异常检出率均显著高于汉族(P<0.001),藏族男性中年组和女性青年组、中年组TG异常检出率反而比汉族高(P<0.001、P<0.05、P<0.001);汉族男性青年组、中年组、老年前期组HDL-C异常检出率明显高于藏族(P<0.001)。结论藏族是混合型高脂血症的高危人群,尤其藏族男性;汉族男性是低HDL-C血症的高危人群。

Objective To investigate the differences in blood lipid levels between Tibetan and Han people in Lhasa,China. Methods A total of 1 228 people（Tibetan 559,Han 669） were randomly selected.The serum lipids included total cholesterol（TC）,triglycerin（TG）,low-density lipoprotein cholesterol（LDL-C）,and high-density lipoprotein cholesterol（HDL-C） were tested according to China Adult Dyslipidemia Prevention Guide,2007.And then the comparison of misdetection rate were made.The results were compared by Covariance Analysis. Results Han serum TG was higher than Tibetan（P≤0.001）,while HDL-C was lower than their counterpart（P0.001）.Tibetan serum TC and LDL-C were higher than those in Han（P0.001）.The misdetection rate of dyslipidemia in some Tibetan male adults was higher than that in Han（P0.001）.TG levels in female Tibetan and some male Tibetan were also higher than that in Han（P0.001）.Meanwhile,the misdetection rate of HDL-C levels in male Han adult was significantly higher than those of the Tibetan（P0.001）. Conclusions The Tibetan is high risk people of developing complication of dyslipidemia,especially in male.However,male Han is high risk group of developing lower HDL-C.