摘要
Aplastic anemia （AA） is an acquired disorder in which .bone marrow fails to produce or release sufficient amounts of blood cell. Antiphospholipid syndrome （APS） is an autoimmune disease characterised by recurrent arterial or venous thrombosis, pregnancy morbidity and the persistence of positive antiphospholipid antibodies （aPL）, including anticardiolipin antibody （ACL） and lupus anticoagulant （LA）. 1 The most prevalent neurologic manifestation of APS is cerebrovascular ischemic events due to arterial thromboses. The deep veins of lower extremities are commonly involved in venous thrombosis of APS, but cerebral venous sinus thrombosis is rare with only several cases reported.2-11 AA together with APS is extremely rare.12 Here we report a case of cerebral venous sinus thrombosis in an AA patient with APS.
Aplastic anemia （AA） is an acquired disorder in which .bone marrow fails to produce or release sufficient amounts of blood cell. Antiphospholipid syndrome （APS） is an autoimmune disease characterised by recurrent arterial or venous thrombosis, pregnancy morbidity and the persistence of positive antiphospholipid antibodies （aPL）, including anticardiolipin antibody （ACL） and lupus anticoagulant （LA）. 1 The most prevalent neurologic manifestation of APS is cerebrovascular ischemic events due to arterial thromboses. The deep veins of lower extremities are commonly involved in venous thrombosis of APS, but cerebral venous sinus thrombosis is rare with only several cases reported.2-11 AA together with APS is extremely rare.12 Here we report a case of cerebral venous sinus thrombosis in an AA patient with APS.
