大柴胡汤加潜阳丹治疗急性重症胰腺炎临床观察

Clinical Observation of Da Chaihu Decoction Combined with Qianyang Pellet for Treatment of Acute Severe Pancreatitis

目的:对比观察大柴胡汤与大柴胡汤加潜阳丹治疗急性重症胰腺炎的疗效。方法:将36例急性重症胰腺炎患者随机分为对照组、治疗组各18例,分别观察治疗后2组患者的住院期间病死率、住院平均时间、脏器功能衰竭发生率,以及腹胀消失时间及血、尿淀粉酶,C反应蛋白、白细胞。结果:治疗组病死率与对照组比较,差异无显著性意义(P>0.05)。2组治愈患者住院时间比较,差异有显著性意义(P<0.05)。治疗组脏器功能衰竭发生率与对照组比较,差异无显著性意义(P>0.05)。2组治愈患者腹胀消失时间和C反应蛋白、白细胞恢复正常时间比较,差异均有显著性意义(P<0.05)。结论:在西医治疗基础上,使用大柴胡汤加潜阳丹治疗急性重症胰腺炎有效,且其疗效优于单用大柴胡汤。

Objective:To observe the therapeutic effect of Da Chaihu Decoction(DCD) combined with Qianyang Pellet(QP) for the treatment of acute severe pancreatitis.Methods:Thirty-six acute severe pancreatitis patients were equally randomized into control group and treatment group.On the basis of routine western medical treatment,the control group was given DCD,and the treatment was given DCD combined with QP.After treatment,we observed case fatality rate during hospitalization,average hospitalization time,incidence of organ failure,time for the disappearance of abdominal distension,blood and urine amylase level,C-reactive protein content,white blood cell count.Results:The differences of case fatality rate and incidence of organ failure were insignificant between the two groups(P > 0.05),while the differences of average hospitalization time,time for the disappearance of abdominal distension,and time for C-reactive protein content and white blood cell count becoming normal were significant between the two groups(P < 0.05).Conclusion:On the basis of routine western medical treatment,DCD combined with QP is effective for the treatment of acute severe pancreatitis,and is superior to DCD alone.