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冠心病患者对比剂诱发肾病的临床研究 被引量：2

Clinical Study of Contrast-induced Nephropathy in Patients with Coronary Heart Disease
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摘要 为了比较两种水化方法对对比剂肾病(CIN)的影响,我们选住院行经皮冠状动脉介入治疗(PCI)94例肾功能不全患者,随机分为氯化钠水化组、碳酸氢钠水化组测定术后4天血肌酐水平变化。结果显示,氯化钠水化组6例发生CIN(13.3%),碳酸氢钠水化组3例CIN(6.3%),提示对于慢性肾功能不全患者碳酸氢钠水化方案更优。 To compare the two methods of hydration in effect of renal function of contrast--induced nephropathy （CIN）. 94 cases of patients with renal failure were randomly divided into two groups：saline hydration treatment group and sodium bicarbonate hydration treatment group, serum creatinine was measured at 96 hours after percutaneous coronary intervention （PCI）. 6 cases of sodium chloride hydration occurred CIN （ 13.3M ）, sodium bicarbonate hydration group of three cases of CIN （ 6.3 % ）. Therefore, the preventive therapeutic effect of sodium bicarbonate hydration in CIN is better than saline hydration
作者 周庆国 朱志勇
机构地区 河南省平煤医疗集团总医院心内科
出处 《医学与哲学（B）》 2010年第9期24-25,共2页 Medicine & Philosophy(B)
关键词 对比剂肾病 氯化钠水化 碳酸氢钠水化 PCI contrast-induced nephropathy, saline hydration, sodium bicarbonate hydrationd, percutaneous coronary intervention
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献10

  • 1Mehran R,Aymong E D,Nikolsky E, et al. A simple risk score for prediction of contrast--induced nephropathy after percutaneous cornary intervention=developmentand initial validation[J]. J Am Coll Cardio,2004,44(7): 1393 -1399.
  • 2Gruberg L, Mehran R,Dangas G,et al. Acute renal failure requiring dialysis after percutaneous coronary interventions[J]. Catheter Cardiovas Interven,2001 52:409 --416.
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  • 5Merten G J,Burgess W P,Gray L V, et al. Prevention of contrastinduced nephropathy with sodium bicarbonate.- a randomized controlled trial[J]. JAMA,2004, 291(19): 2328--2334.
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  • 7Frank H, WernerD, Lorusso V, et a. l Simultaneous hemodialysis during coro nary angiography fails to prevent radiocontrast-- induced nephropathy in chronic renal failure[J]. ClinNephrol, 2003, 60(3): 176- 182.
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二级参考文献19

  • 1Briguori C,Airoldi F, Morici N, et al. New fharmacological protocols toprevent or reduce contrast media nephropathy[J].Minerva Cardioangiul, 2005,53 ( 1 ) : 49-- 58.
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  • 4Rihal C S,Textor S C,Grill D E,et al. Incidence and prognostic importance of acute renal failure after pereutaneous coronary intervention[J]. Circulation,2002,105(19) :2259--2264.
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共引文献18

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医学与哲学（B）
2010年 第9期

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