脑动静脉畸形手术前后血流灌注的TCD研究

A study on Blood Perfusions in Preoperative and Postoperative Cerebral Arteriovenous Malformation by TCD

对脑AVM患者手术前后进行TCD检查以及激光多普勒监测,以探讨脑AVM患者血流动力学指标与手术后局部脑皮层血流量指标变化的相关性,从而为预测正常灌注压突破综合征提供依据。结果显示AVM患者高流量组与低流量组之间手术后rCBF值存在显著差异(P<0.05),并且不同流量AVM供血动脉的血流动力学指标差异性于手术后消失。因此,通过对AVM患者手术前后TCD监测,有助于为预测术后局部脑皮层血流量变化提供依据。

By perioperatively monitoring patients of cerebral arteriovenous malformation with the transcranial Doppler （TCD） and laser Doppler, we investigate the correlation between the hemodynamic indices of the cerebral arteriovenous malformation and the regional cerebral blood flow （rCBF） of AVM patients perioperatively, in order to provide evidence for predicting NPPBS. There is significant difference in the postoperative rCBF between the high flow group and the low blood flow group（P〈0.05）. And there are preoperatively significant differences of blood supply for AVM between the high flow group and the low flow group, and the differences disappear after operation. By monitoring the changes of perioperative TCD hemodynamic indices and regional cerebral blood flows for patients of AVM, we have more farreaching understanding of the perioperative hemodynamics for AVM and provide the evidence for preventing NPPBs effectively.