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支气管哮喘病人外周血单核/巨噬细胞IL-15的分泌水平 被引量:1

Levels of IL-15 in supernatant of monocytes/macrophages in patients with bronchial asthma
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摘要 目的和方法:利用改良的MTT比色法测定CTLL2细胞增殖程度而确定IL-15水平的方法,测定了27例支气管哮喘急性发作期病人和40例健康人外周血单核/巨噬细胞培养上清中IL-15的分泌水平。结果:无论刺激与否,哮喘病人IL-15水平均高于健康对照组,两组差异显著(P<005)。 AIM and METHODS: Interleukin (IL-15) is a newly described cytokine with an action similar to that of IL-2. In this study, the levels of IL-15 in the supernatants of LPS-stimulated (or not) monocytes/macrophages were examined in 27 patients with bronchial ashma at acute phase, and were compared with healthy controls. RESULTS:Signifcant elevation of IL-15 was observed in supernatants of monocytes/macrophages from patients with asthma as compared with that in normal individuals, whether LPS existed or not.CONCLUSION:IL-15 plays a role in asthma.
出处 《中国病理生理杂志》 CAS CSCD 北大核心 1999年第7期626-627,共2页 Chinese Journal of Pathophysiology
关键词 白细胞介素15 单核细胞 巨噬细胞 哮喘 Interleukin-15 Monocytes Macrophages Asthma
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参考文献2

  • 1中华结核和呼吸杂志编辑委员会.支气管哮喘的定义、诊断、分期和疗效的评定标准(试行草案)[J].中华结核和呼吸杂志,1993,16:5-5.
  • 2中华结核和呼吸杂志编委会,中华结核和呼吸杂志,1993年,16卷,哮喘增刊,5页

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