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乳及乳制品中朊蛋白及其安全性研究进展 被引量：2

Prion Proteins and Their Safety in Milk and Milk Products
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摘要 朊蛋白(prion proteins,PrP)是近年来确认的引起人畜共患病的新型蛋白质类传染源,其在乳及乳制品中的存在直接关系到乳产品安全和人类健康。本文对朊蛋白生物学特点、乳及乳制品中朊蛋白的来源和含量以及安全性进行了综述,以便为乳制品加工和安全评价提供参考。 Prion proteins were regarded as newly sources of infection that resulted in zoonosis. The safety of prion proteins in milk and milk products has a directly relationship with milk safety and human health. In this paper, the biological character, source and content of prion proteins in milk and milk products and their safety were reviewed. The aim of this paper is to provide reference to the milk processing and safety evaluation. [Chinese Journal of Animal Nutrition, 2010,22（5）：1177-1180]
作者 管峰 石国庆 赵进 杨利国
机构地区 中国计量学院生命科学学院 新疆生产建设兵团绵羊繁育生物技术重点实验室 华中农业大学农业动物遗传育种与繁殖教育部重点试验室
出处 《动物营养学报》 CAS CSCD 北大核心 2010年第5期1177-1180,共4页 CHINESE JOURNAL OF ANIMAL NUTRITION
基金 国家自然科学基金(C120103) "863"科技计划资助项目(2008AA101011)
关键词 朊蛋白 乳 乳制品 安全性 prion proteins milk milk products safety
分类号 Q51 [生物学—生物化学]
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参考文献29

  • 1TAYLOR J P,HARDY J,FISCHBECK K H.Toxic proteins in neurodegenerative disease[J].Science,2002,296(5575):1991-1995.
  • 2LEE I Y,WESTAWAY D,SMIT A F,et al.Complete genomic sequence and analysis of the prion protein gene region from three mammalian species[J].Genome Research,1998,8(10):1022-1037.
  • 3SPARKES R S,SIMON M,COHN V H,et al.Assignment of the human and mouse priori protein genes to homologous chromosomes[J].Proceedings of the National Academy of Sciences,1986,83 (19):7358-7362.
  • 4IANNUZZI L,DI MEO G P,PERUCATTI A,et al.Comparative FISH mapping in river buffalo and sheep chromosomes:assignment of forty autosomal type I loci from sixteen human chromosomes[J].Cytogenetics and Cell Genetics,2001,94 (1/2):43-48.
  • 5CHOI S H,KIM I C,KIM D S,et al.Comparative genomic organization of the human and bovine PRNP locus[J].Genomics,2006,7(5):598-607.
  • 6WATT N T,ROUTLEDGE M N,WILD C P,et al.Cellular prion protein protects against reactive oxygen species induced DNA damage[J].Free Radical Biology and Medicine,2007,43(6):959-967.
  • 7管峰,潘磊,石国庆,刘守仁,杨利国.绵羊PRNP遗传多样性与抗病育种研究进展[J].遗传,2009,31(2):137-141. 被引量：14
  • 8HETZ C,MAUNDRELL K,SOTO C.Is loss of function of the prion protein the cause of prion disorders ?[J].Trends in Molecular Medicine,2003 (9):237-243.
  • 9BROWN D R,SCHMIDT B,KRETZSCHMAR H A.Effects of oxidative stress on prion protein expression in PC12 cells[J].International Society of Developmental Neuroscience,1997,15:961-972.
  • 10WONG B S,LIU T,LI R,et al.Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein[J].Journal of Neurochemistry,2001,76:565-572.

二级参考文献128

共引文献29

同被引文献39

  • 1Maddison BC, Rees HC, Baker CA, Taema M, Bellworthy SJ, Thome L, et al. Prions are secreted into the oral cavity in sheep with preclinical scrapie. JInfect Dis 2010; 201(11): 1672-6.
  • 2Gough KC, Maddison BC. Prion transmission: Prion excretion and occurrence in the environment. Prion 2010; 4(4): 275-82.
  • 3Prusiner SB. Prions. Proc Nat! Acad Sci USA 1998; 95(23): 13363-83.
  • 4Saborio GP, Permanne B, Soto C. Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 2001; 411(6839): 810-3.
  • 5ZOU WQ, Gambetti P. From microbes to prions: the final proof of the prion hypothesis. Cell 2005; 121(2): 155-7.
  • 6Abid K, Morales R, Soto C. Cellular factors implicated in prion replication. FEBS Lett 2010; 584(11): 2409-14.
  • 7Gonzalez-Montalban N, Makarava N, Ostapchenko VG, Savtchenk R, Alexeeva I, Rohwer RG, et al. Highly efficient protein misfolding cyclic amplification. PLoS Pathog 2011; 7(2): e1001277.
  • 8Pulford B, Spraker TR, Wyckoff AC, Meyerett C, Bender H, Ferguson A, et al. Detection of PrPCWD in feces from naturally exposed Rocky Mountain elk (Cervus elaphus nelson i) using protein misfolding cyclic amplification. J Wildl Dis 2012; 48(2): 425-34.
  • 9Barria MA, Gonzalez-Romero D, Soto C. Cyclic amplification of prion protein misfolding. Methods Mol Bioi 2012; 849: 199-212.
  • 10Atarashi R. Recent advances in cell-free Prps, amplification technique. Protein Pept Lett 2009; 16(3): 256-9.

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动物营养学报
2010年 第5期

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