两组中西医结合方案治疗急性脑梗死的临床观察

Clinical Study of Acute Cerebral Infarction Treated with Two DifferentPrograms of Integrated Traditional and Western Medicine

目的：观察两组中西医结合方案对急性脑梗死的治疗效果。方法：选择８４例患者，随机分为两组，Ⅰ组４４例，采用前列腺素Ｅ１注射液、血塞通注射液治疗，Ⅱ组４０例，采用低分子右旋糖酐注射液配川芎嗪注射液治疗，于１个月后进行疗效评定，并观察治疗前后血脂水平及血液流变学的变化。结果：Ⅰ组与Ⅱ组比较总有效率有显著性差异（Ｐ＜００５），基本治愈＋显著进步率有非常显著性差异（Ｐ＜００１）。两组治疗前血脂紊乱，血粘度偏高，治疗后均有不同程度的改善，但Ⅰ组优于Ⅱ组，两组比较部分指标有显著或非常显著性差异（Ｐ＜００５；Ｐ＜００１）。结论：采用前列腺素Ｅ１注射液、血塞通注射液治疗急性脑梗死具有较明显改善临床症状，减少神经功能缺损积分的作用，对调整血脂，降低血粘度亦有较好的作用。

Purpose: To study the therapeutic effect on acute cerebral infarction through two different programs of integrated western and traditional chinese medicine. Methods: 84 cases randomly chosen were made into two groups. Group I with 40 cases was treated with prostaglandin E1 Injection together with Xue Sai Tong Injection, while Group II with 40 cases with low molecular dextran Injection and Chuan Xiong Qin Injection. The effect was evaluated one month after the treatment and the observation was made on the changes of blood-lipid level and blood rheology. Results: The total effective rate was significantly different (P<0.05) between the two groups, with the very obvious difference in the fundamental recovery rate and significant improvement rate (P<0.01). The cases in Group had the problems of blood-lipid disturbance and high blood viscosity before the treatment. But those problems were improved at different levels after the treatment and Group I achieved better effects than Group . Most of ; TCM-WM therapythe index in Group had significant and extremely significant difference(P<0.05; P<0.01). Conclusions: The treatment of acute cerebral infarction with prostaglandin E1 Injection and Xue Sai Tong Injection can significantly improve the clinical symptoms, regulate blood-lipid and lower blood viscosity and disablement rate.\=