丁苯羟酸合成方法的改进

Improvement on Synthesis of Bufemaxac

以对羟基苯乙酰胺为原料，经烷基化、水解、酯化、氧肟化等４步反应合成丁苯羟酸，总收率为４６．５％。

With pHydroxybenzeneactamide as the starting material,the Bufemaxac was prepared by means of four steps reaction of alkylation,hydrolyzing,esterification and Ooximation with total yield of 46.5%.