经前综合征患者月经周期中血清Ca^(2+) Mg^(2+)水平变化的研究

A Studies on the Change of Serum Ca2+ Mg2+ Level of the Patients with premenstrual Syndrome

测定经前综合征（ＰＭＳ）患者月经各时期血Ｃａ２＋、Ｍｇ２＋水平，探讨其在ＰＭＳ发生发展中的作用。结果发现ＰＭＳ妇女各期Ｅ２、Ｐ变化与正常妇女无显著差异，卵泡期有较高的Ｍｇ２＋水平，黄体期明显降低，同时Ｃａ２＋／Ｍｇ２＋比值增高（Ｐ＜０．０５），而正常妇女各期Ｍｇ２＋水平与Ｃａ２＋／Ｍｇ２＋比值无显著差异。提示黄体期血Ｍｇ２＋水平降低和Ｃａ２＋／Ｍｇ２＋比值升高可能与ＰＭＳ症状有关。

In order to investigate the correlation of serum Ca2+Mg2+level with premenstrual syndrome(PMS),we measured Ca2+Mg2+level in different stage of a menstrual cycle.The results showed that the change of E2 and P was the same in the normal women and the women with PMS. There was a higher Mg2+level at follicle stage in the women with PMS,Mg2+level decreased and Ca2+/Mg2+ratio increased obviously (P<0.05). But there was no significant difference in the Mg2+level and Ca2+/Mg2+ratio in normal women. It is suggested the decreasing Mg2+level and increasing Ca2+/Mg2+ratio may be a cause of PMS. This is useful to the diagnosis and therapy to PMS.