贫血与非贫血孕妇微营养素状况的研究

Micronutrient status in anemic and non-anemic women in the third trimester of pregnancy

目的：调查孕晚期贫血与非贫血妇女微营养状况。方法：在我国东北、西北、东南、西南各取一个调查点,对象为市、区级医院及保健院的常规孕检妇女。734例年龄段在20-35岁的孕晚期妇女被随机抽出作为调查对象。血红蛋白浓度小于110 g/L被分在贫血组,大于110 g/L为对照组。测定血清中的维生素A、C、B12、铁和锌。结果：贫血孕妇血清铁盒微营养素水平显著低于非贫血孕妇,贫血孕妇血清铁为909μg/L（非贫血组1109μg/L）,铁蛋白13.8μg/（非贫血组19.6μg/L）,维生素C 308.9μg/L（非贫血组388.1μg/L）,维生素A 50.0μg/d l（非贫血组59.3μg/d l）。结论：孕晚期妇女贫血可能与铁、维生素A、C等缺乏有关。晚孕妇女应该从食物上增加铁、维生素A、C的摄取量。也可额外补充铁和维生素制剂以预防孕晚期贫血的发生。

Objective： To investigate the micronutrient status of anemic and non-anemic pregnant women.Methods： 734 pregnant women in the third trimester aged 20~35,were randomly recruited in the Northeast,Northwest,Southeast and Southwest of China.Women with Hb110 g/L were in the anemic group;women with Hb110 g/L were in the control group.Serum concentrations of Vitamin A,Vitamin C,Vitamin B12,iron and zinc status parameters were determined.Results： Serum concentrations of iron and micronutrients were significantly lower in anemic women than in non-anemic women that： ① serum iron： 909μg/L vs 1109 μg/L.② Ferritin： 13.8 μg/L vs 19.6 μg/L.③ Vitamin C： 308.9 μg/L vs 388.1 μg/L.④Vitamin A： 50.0 μg/dl vs 59.3 μg/dl.Conclusion： Iron,Vitamin A and Vitamin C deficiencies would lead to anemia of pregnant women in the third trimester.Food-based or supplement-based approaches trying to increase the intake of iron and certain vitamins may benefit to decrease anemic in pregnant women in the third trimester.