水样中氟罗沙星和磺胺喹噁啉的离子液体均匀提取

Homogeneous Ionic Liquid Microextraction of Fleroxacin and Sulfaquinoxaline from Water Samples

提出一种新的离子液体均匀提取方法,即向水样中加入可溶于水的离子液体1-己基-3-甲基咪唑四氟硼酸盐([C6MimBF4]),再加入过量六氟磷酸铵(NH4PF6),形成不溶于水的离子液体1-己基-3-甲基咪唑六氟磷酸盐([C6MimPF6]),水样中的氟罗沙星和磺胺喹噁啉被提取到[C6MimPF6]相,离心分离后,离子液体可直接用于HPLC分析.本法测得的氟罗沙星和磺胺喹噁啉的检出限分别为1.8和1.1μg/L.

The homogeneous liquid microextraction was developed for extracting fleroxacin and sulfaquinoxaline from water samples. A room temperature ionic liquid [C6MImBF4],which is dissolvable in water,and NH4PF6,can be sequentially added into the water samples. The resulting [C6MImPF6],which is not dissolvable in water,can be dispersed in the sample solution as very fine drops. After extraction,phase separation was performed by centrifugation. The sedimented phase was taken with a HPLC microsyringe and injected into the high performance liquid chromatography（ HPLC） system for analysis. The detection limits for fleroxacin and sulfaquinoxaline were found to be 1. 8 and 1. 1 μg/L,respectively.