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结核感染T细胞斑点试验在结核性脑膜炎早期诊断中的意义 被引量:18

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摘要 结核性脑膜炎(tuberculous meningitis,TBM)占结核病的10%~20%,是常见严重的肺外结核病,其预后与早期诊断及治疗密切相关.结核感染T细胞斑点(T-SPOT-TB)试验是利用酶联免疫斑点法(ELISPOT)检测感染者的特异性T细胞来诊断结核病的一种新方法,利用结核分枝杆菌感染者外周血单个核细胞(PBMC)中存在结核感染特异性T细胞,这些T细胞在受到致病性结核分枝杆菌特异抗原刺激后分泌IFN-γ而设计的试验.
出处 《中华传染病杂志》 CAS CSCD 北大核心 2010年第8期504-506,共3页 Chinese Journal of Infectious Diseases
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