睡眠质量与社区人群肠易激综合征相关性分析

Association of sleep quality with irritable bowel syndrome in community

目的探讨上海市社区人群睡眠质量与肠易激综合征（IBS）患病率及两者之间的关系。方法采用随机分层整群抽样方法，对上海市嘉定区江桥镇常住人群成年居民进行面访式问卷调查，回收有效调查问卷11569份。采用罗马Ⅲ标准诊断IBS，阿森斯睡眠障碍量表进行自我评估，分析睡眠障碍与IBS之间的关系。结果睡眠障碍在社区总人群、IBS患者及非IBS患者中发生率分别为21．oo％、33．02％和18．74Voo。IBS组存在睡眠障碍比例高于非IBS组，两组间差异有统计学意义（P=0．004，（OR=2．14，95％CI：1．92～2．39），即存在睡眠障碍的人群患IBS的危险性是无睡眠障碍人群的2．14倍。在IBS组，女性患者存在睡眠障碍的比例（37．24％）显著高于男性患者（28．41％），两组间差异有统计学意义（P=0．000，OR—1．50，95％CI：1．23～1．82），提示存在睡眠障碍的女性更易于患IBS。Logistic回归分析显示睡眠障碍是IBS的危险因素之一（OR=2．11，95％CI：1．89～2．36）。结论IBS患者常存在睡眠障碍，尤其是女性患者。

Objective To investigate the association of sleep quality with prevalence of irritable bowel syndrome （IBS） in communities of Shanghai. Methods A survey on prevalence of IBS in communities of Jiangqiao County, Jiading District of Shanghai was conducted using a stratified, randomized cluster-sampling method. A total of 11 569 questionnaires was collected. The IBS was diagnosed according to Rome Ⅲ criteria, and Athens Insomnia Scale （AIS） was used for selfassessment. The relationship between sleep quality and IBS was analyzed. Results The prevalence of insomnia was 21. 00% in community groups, 33. 02% in IBS patients and 18. 74% in non-IBS patients. The incidence of insomnia was significant higher in IBS group than non-IBS group （P=0. 004,0R= 2.14,95% CI： 1.92-2.39）. Among IBS patients, the incidence of insomnia was higher in females than in males （37. 24% vs 28. 41%,P=0. 000）. A logistic analysis for psychological contributing factors in IBS revealed that insomnia might be one of the risk factors for IBS （OR： 2. 11, 95%CI：1. 89-2. 36）, Conclusion IBS patients have poor sleep quality,especially in females.