我国A群牛轮状病毒感染的血清流行病学调查

Seroepidemiological survey of the group A bovine rotavirus infection in China

为调查A群牛轮状病毒(BRV)在我国不同地区牛群中的感染和流行情况,本研究采用间接ELISA检测2005年～2006年期间在我国12个不同地区收集的1760份牛血清中抗A群BRV抗体。结果显示,其强阳性血清225份(12.8%);中等阳性血清1240份(70.4%);弱阳性血清279份(15.9%);阴性血清16份(1%)。总抗体阳性率高达99%。不同地区强阳性、中等阳性及弱阳性血清所占比例有所不同。结果表明,A群BRV在我国牛群中的感染和流行不但非常广泛,而且极为严重。本研究对我国BRV感染进行了较大规模的血清流行病学调查,其结果可为我国犊BRV腹泻疾病的防制提供重要的依据。

To investigate the prevalence of group A bovine rotavirus infection in different areas of China,serum samples from 12 different regions of China were collected and subjected to antibody detection by indirect ELISA. Among 1,760 samples tested,12.8% （225/1760） were detected strong positive,70.4% （1240/1760）,moderate positive,15.9% （279/1760）,weak positive,and only 1% （16/1760）,negative. The rate of strong,moderate or weak positive sera varied according to different areas. The results indicated that the infection of the group A bovine rotavirus in China was not only widespread,but also very severe,which imposes great threat to the newborn calves. The large-scale epidemiological survey of the group A bovine rotavirus infection in China provided an important foundation for developing a prophylactic strategy against diarrhea in calves caused by group A bovine rotavirus.