氯己定预防干槽症的循证病案讨论

Evidence-based casuistics of preventing dry socket using Chlorhexidine

目的针对氯己定预防拔牙后干槽症的效果,检索其当前的最佳证据,为其临床合理应用提供依据。方法通过Cochrane图书馆和美国医师协会杂志俱乐部,以氯己定和干槽症为关键词行计算机检索。结果质量分数0.12%的氯己定能有效降低干槽症的发生率,但有关其使用方式和制剂类型的效果比较研究相对较少,证据不够充分,尚需进一步的研究。结论阻生牙拔除术前或术后,质量分数0.12%的氯己定能有效降低干槽症的发生率。

Objective To evaluate effect of Chlorhexidine in preventing dry socket after impacted tooth extraction based on best evidence,and guide its clinical use. Methods Using Chlorhexidine and dry socket as keywords to search evidence-base medicine reviews from Cochrane library and American College of Physicians Journal Club to find the best relevant clinical evidence and evaluate quality of the evidence. Results According to the evidence,Chlorhexidine of mass fraction 0.12% can effectively reduce the incidence of dry socket,but research on the effect of various usage or drug formulations for Chlorhexidine is insufficient,further study is needed. Conclusion Chlorhexidine of mass fraction 0.12% can effectively reduce the incidence of dry socket in im-pacted tooth extraction.