摘要
目的评价噻托溴铵对慢性阻塞性肺疾病(COPD)患者耐力与生活质量的影响。方法48例稳定期COPD患者随机分为噻托溴铵组和对照组(常规治疗组),1、3、6、12和24个月测定6min步行距离试验与COPD健康相关生活质量评估。结果两组患者在治疗后均较治疗前6min步行距离均有显著性增加,健康相关生活质量总评分均较治疗前明显下降,生活质量明显提高,且噻托溴铵组较对照组更为明显。结论噻托溴铵不仅能够明显改善COPD患者的耐力,而且能够明显改善患者的健康相关的生活质量。
【Objective】To explore the effects of tiotropium on patients with chronic obstructive pulmonary dis- ease （COPD）; by analysing exercise tolerance and the score of life quality.【Methods】48 patients with COPD were randomly divided into two groups： tiotropium experimental group and regular treatment control group. All patients underwent 6 minute walk test and the score of life quality before treatment after 1, 3, 6, 12 and 24 months of therapy respectively. 【Results】After 1, 3, 6, 12 and 24 months of therapy respectively, there was improvement of 6 minute walk test and the score of life quality in both groups than before treatment. Tiotropium group was better. 【Conclusion】Tiotropium can improve exercise tolerance and quality of life more significantly.
出处
《中国医学工程》
2009年第4期299-300,共2页
China Medical Engineering
