青年与中老年胃癌的临床病理特点比较

目的比较青年与中老年胃癌的临床及病理特点。方法回顾性分析我院收治的680例胃癌患者的临床资料,将青年患者作为观察组,中老年患者作为对照组,比较两组患者性别构成、胃癌家族史、临床首发症状、确诊时间、病变部位、Borrmann分型、病理类型、分期、转移、治疗方法、生存率等方面上的差异。结果 680例胃癌患者中青年64例,发生率9.41%两组比较观察组女性多、胃癌家族史比例高、临床表现缺乏特异性、确诊时间长、BorrmannⅢ、Ⅳ型为主、以低-未分化腺癌为主、Ⅲ-Ⅳ期居多、转移率高、多选择手术治疗(P>0.05);两组生存期比较无差异(P>0.05)。结论青年人胃癌发生率较高,临床缺乏特异性,具体浸润能力强、恶性度高,进展快、漏诊率高、转移早等等特点,应及时检查诊断,早期行胃镜检查,手术仍然是最有效的治疗手段。

Objective Comparing young and old patients the clinical and pathological features of gastric cancer.Methods Retrospective analysis of 680 cases of our hospital on clinical data,the study group of young patients,in elderly patients in the control group to compare the two groups were gender,family history of gastric cancer,clinical symptom,diagnosis time,lesions,Borrmann type,histological type,stage,metastasis,treatment method,such as differences in survival.Results 680 cases of 64 cases of young patients with gastric cancer incidence 9.41% of women in the two groups over the observation group,a high proportion of gastric cancer family history,clinical manifestation is not specifi c,confi rmed a long time,Borrmann Ⅲ,Ⅳ type mainly to low-undifferentiated adenocarcinoma,Ⅲ-Ⅳ of the majority,transfer rate,multi-choice surgical treatment（P0.05）;the two groups showed no difference in survival（P0.05）.Conclusion Higher incidence of gastric cancer in young,clinical lack of specifi city,the specifi c infi ltration capacity,a vicious high,with rapid,high rate of missed diagnosis,early metastasis,etc,that should be promptly diagnosed,early underwent endoscopy,surgery is still the most effective treatment.